Lin Deng

denglin@szbl.ac.cn

+86 185 8293 1616

ACADEMIC EXPERIENCE

2004 - 2008

2008 - 2010

2010 - 2015

2015 - 2020

2020 - present

B.S.

Biotechnology

Northwest A&F University, China

M.S.

Plant Pathology

Northwest A&F University, China

Ph.D.

Biochemistry

Dartmouth College, USA

Postdoc.

Genome Instability

Harvard Medical School/Dana-Farber Cancer Institute/HHMI, USA

Assistant Professor

Shenzhen Bay Laboratory, China

AWARDS AND HONORS

2024

Guangdong Special Support Plan for Young Scientists

2014

E. Lucile Smith Award for Excellence in Biochemistry, Dartmouth Medical School

2020

Shenzhen High-Caliber Personnel

2014

John H. Copenhaver, Jr. and William H. Thomas, MD 1952 Fellow, Dartmouth College

2015

Chinese Government Award for Outstanding Students Abroad

2017

The International Youth Friend of Shenzhen City, China

2023

Deputy to the People’s Congress of Guangming District, Shenzhen

SELECTED PUBLICATIONS

(#, co-first authors; *, corresponding authors.)

Ye, G.#, He, Y.#, Zhang, Y., Li, D., Liu, F., Li, Y., Ge, Q., Guo, Q., Han, S., Song, C., Chang, W., Zhang, H., Peng, Q., Sun, K., Ji, W., and Deng, L.* (2025) Mitotic DNA repair by TMEJ suppresses replication stress-induced nuclear envelope reassembly defect. Nature Communications, 16, 8836. PMID: 41044090

Wang, J.,# Xiong, J.,# Zhang, S., Li, D., Chu, Q., Chang, W., Deng, L.*, and Ji, W.* (2024) A complex containing RhoBTB3-SHIP164-Vps26B promotes the biogenesis of early endosome buds at Golgi-endosome contacts. Cell Discovery, 10, 38. PMID: 38565878

Chen, H.,# Wang, Z.,# Gong, L., Wang, Q., Chen, W., Wang, J., Ma, X., Ding, R., Li, X., Zou, X., Plass, M., Lian, C., Ni, T., Wei, G., Li, W.,* Deng, L.*, and Li, L.* (2024) A distinct class of pan-cancer susceptibility genes revealed by alternative polyadenylation transcriptome-wide association study. Nature Communications, 15, 1729. PMID: 38409266

Chu, Q.,# Wang, J.,# Du, Y., Zhou, T., Shi, A., Xiong, J.,* Ji, W.,* and Deng, L.* (2022) Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions. Cell Death & Differentiation, 30(1):94-110. PMID: 35962186

Deng, L., Wu, R.A., Sonneville, R., Kochenova, O.V., Labib, K., Pellman, D., and Walter, J.C. (2019). Mitotic CDK promotes replisome disassembly, fork collapse, and complex DNA rearrangements. Molecular Cell, 73(5):915-929.e6. PMID: 30849395.

Deng, L., Lee, M.E. Schutt K.L., and Moseley, J.B. (2017). Phosphatases generate signal specificity downstream of Ssp1 kinase in fission yeast. Molecular and Cellular Biology, 37:e00494-16.doi: 10.1128/MCB.00494-16. PMID: 28223368.

Deng, L., Baldissard, S., Kettenbach, A.N., Gerber, S.A., and Moseley, J.B. (2014). Dueling kinases regulate cell size at division through the SAD kinase Cdr2. Current Biology 24, 428-433. PMID: 24508166.

Deng, L., Kabeche, R., Wang, N., Wu, J.Q., and Moseley, J.B. (2014). Megadalton node assembly by binding of Skb1 to the membrane anchor Slf1. Molecular Biology of the Cell 25, 2660-2668. PMID: 25009287.

Deng, L., and Moseley, J.B. (2013). Compartmentalized nodes control mitotic entry signaling in fission yeast. Molecular Biology of the Cell 24, 1872-1881. PMID: 23615447.

Google Scholar: https://scholar.google.com/citations?hl=zh-CN&authuser=1&user=HE-7srMAAAAJ

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Cell Cycle and Genome Instability